نمایش مبدأ برای الگو:Drugbox/توضیحات

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{{Documentation subpage}}
{{Intricate template}}

The '''[[Template:Drugbox]]''' provides a consistent layout for drug articles and an interface to other sources that provide information about the drug. It can be used for single drugs, combination products (see [[#Combination products]]), monoclonal antibodies (see [[#Monoclonal antibody drugs]]) and vaccines (see [[#Vaccines]]). Don't worry about trying to fill in all the fields &ndash; even specifying just one or two can be useful.

===Single chemical drugs===

While editing a drug page, copy and paste either style of the following text at the top of the page:

'''Shortened single-drug form:''' &nbsp; <small>(For visibility, vertical-bar pipes "|" start a line but can also end a line.)</small>
<pre>
{{Drugbox
| drug_name         = 
| IUPAC_name        = 
| image             = 
| alt               = 
| caption           = 

<!-- Clinical data -->
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| pregnancy_AU      = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US      = <!-- A / B            / C / D / X -->
| pregnancy_category= 
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_status      = 
| routes_of_administration = 

<!-- Pharmacokinetic data -->
| bioavailability   = 
| protein_bound     = 
| metabolism        = 
| elimination_half-life = 
| excretion         = 

<!-- Identifiers -->
| CAS_number        = 
| ATCvet            = 
| ATC_prefix        = <!-- 'none' if uncategorised -->
| ATC_suffix        = 
| PubChem           = 
| DrugBank          = 

<!-- Chemical data -->
| chemical_formula  = 
| molecular_weight  = 
}}
</pre>

'''Full single-drug template''' with extended fields:
<pre>
{{Drugbox
| IUPAC_name        = 
| image             = 
| width             = 
| alt               = 
| image2            = 
| width2            = 
| alt2              = 
| imagename         = <!-- else may use drug_name -->
| drug_name         = <!-- else may use imagename -->
| caption           = 

<!-- Clinical data -->
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| licence_EU        = <!-- EMA requires brand name -->
| licence_US        = <!-- FDA may use generic name -->
| DailyMedID        = <!-- preference to licence_US -->
| pregnancy_AU      = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US      = <!-- A / B            / C / D / X -->
| pregnancy_category= 
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_status      = 
| dependency_liability = 
| routes_of_administration = 

<!-- Pharmacokinetic data -->
| bioavailability   = 
| protein_bound     = 
| metabolism        = 
| elimination_half-life = 
| excretion         = 

<!-- Identifiers -->
| CAS_number        = 
| CAS_supplemental  = 
| ATCvet            = 
| ATC_prefix        = <!-- 'none' if uncategorised -->
| ATC_suffix        = 
| ATC_supplemental  = 
| PubChem           = 
| PubChemSubstance  = 
| IUPHAR_ligand     = 
| DrugBank          = 
| ChemSpiderID      = 
| UNII              = 
| KEGG              = 
| ChEBI             = 
| ChEMBL            = 
| synonyms          = 

<!-- Chemical data -->
| chemical_formula  = 
| C= | H= | Ag= | As= | Au= | B= | Bi= | Br= | Cl= | Co= | F= | Fe= | Gd= | I=
| K= | Mn= | N= | Na= | O= | P= | Pt= | S= | Sb= | Se= | Sr= | Tc= | Zn= | charge=
| molecular_weight  = 
| smiles            = 
| StdInChI          = 
| StdInChI_comment  = 
| StdInChIKey       = 
| density           = 
| melting_point     = 
| melting_high      = 
| melting_notes     = 
| boiling_point     = 
| boiling_notes     = 
| solubility        = 
| specific_rotation = 
| sec_combustion    = 
}}
</pre>

'''OR alternatively:''' use [[User:Diberri|Diberri's]] excellent [http://diberri.dyndns.org/wikipedia/templates/index.html?type=drugbank Wikipedia template filling tool] which will generate a populated template to copy & paste into an article if given a [[DrugBank]] ID number (which may be obtained from [http://redpoll.pharmacy.ualberta.ca/drugbank/ DrugBank search]). Please select for ''Fill template vertically'', but as Wikipedia is a general encyclopedia, most drugs do not warrant ''Show extended fields''.

===Combination products===

Set the parameter '''type=combo'''. This form of the drugbox uses a different subset of parameters. For drug-combinations, at least two components must be defined, with optional 3rd or 4th components. For each component:
* define its name (which will be automatically wikilinked)
* and the class of agent it belongs to but this usually needs manual wikilinking, e.g. for [[Seretide]]:

{{Drugbox
| type       = combo
| drug_name  = Seretide
| component1 = Fluticasone
| class1     = [[گلوکوکورتیکوئید]] 
| component2 = Salmeterol 
| class2     = [[Beta2-adrenergic receptor agonist|Long-acting beta2 agonist]]
}}
<pre>
| type       = combo
| drug_name  = Seretide
| component1 = Fluticasone
| class1     = [[گلوکوکورتیکوئید]]
| component2 = Salmeterol 
| class2     = [[Beta2-adrenergic receptor agonist|Long-acting beta2 agonist]]
</pre>

Generally combination articles will not need to display the molecular images of its constituents (the relevant specific articles would have the images). It disables all Chemical & Pharmacology parameters (which describe properties of single drug items). These redundant disabled parameters are best not included in the template calling, so use the following abridged forms of the template:

'''Shortened combination product form:'''
<pre>
{{Drugbox
| type              = combo
| component1        = <!-- Drugname, automatically linked -->
| class1            = <!-- Group, manual link using [[..|..]] -->
| component2        = <!-- Drugname, automatically linked -->
| class2            = <!-- Group, manual link using [[..|..]] -->

<!-- Clinical data -->
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| pregnancy_AU      = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US      = <!-- A / B            / C / D / X -->
| pregnancy_category= 
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_status      = 
| routes_of_administration = 

<!-- Identifiers -->
| CAS_number        = 
| ATCvet            = 
| ATC_prefix        = <!-- 'none' if uncategorised -->
| ATC_suffix        = 
| PubChem           = 
| DrugBank          = 
}}
</pre>

'''Full combination product template''' with extended fields and allowing for up to 4 items:
<pre>
{{Drugbox
| type              = combo
| drug_name         = 
| component1        = <!-- Drugname, automatically linked -->
| class1            = <!-- Group, manual link using [[..|..]] -->
| component2        = <!-- Drugname, automatically linked -->
| class2            = <!-- Group, manual link using [[..|..]] -->
| component3        = <!-- Drugname, automatically linked -->
| class3            = <!-- Group, manual link using [[..|..]] -->
| component4        = <!-- Drugname, automatically linked -->
| class4            = <!-- Group, manual link using [[..|..]] -->

<!-- Clinical data -->
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| licence_EU        = <!-- EMA requires brand name -->
| licence_US        = <!-- FDA may use generic name -->
| DailyMedID        = <!-- preference to licence_US -->
| pregnancy_AU      = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US      = <!-- A / B            / C / D / X -->
| pregnancy_category= 
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_status      = 
| dependency_liability = 
| routes_of_administration = 

<!-- Identifiers -->
| CAS_number        = 
| CAS_supplemental  = 
| ATCvet            = 
| ATC_prefix        = <!-- 'none' if uncategorised -->
| ATC_suffix        = 
| ATC_supplemental  = 
| PubChem           = 
| PubChemSubstance  = 
| IUPHAR_ligand     = 
| DrugBank          = 
| ChemSpiderID      = 
| UNII              = 
| KEGG              = 
| ChEBI             = 
| ChEMBL            = 
| synonyms          = 
}}
</pre>

===Monoclonal antibody drugs===

Set the parameter '''type=mab'''. This form of the drugbox uses a different subset of parameters, '''mab_type''', '''source''' and '''target''':

{{Drugbox
| type       = mab
| drug_name  = Catumaxomab
| mab_type   = 3funct
| source     = axo
| target     = [[EpCAM]], [[CD3 (immunology)|CD3]]
}}
<pre>
| type       = mab
| drug_name  = Catumaxomab
| mab_type   = 3funct
| source     = axo
| target     = [[EpCAM]], [[CD3 (immunology)|CD3]]
</pre>

'''mab_type''' defines one of the following types of antibody or antibody fragment:
{| class = "wikitable"
|-
! mab_type || output
|-
| mab || Whole antibody
|-
| Fab || [[Fab fragment]]
|-
| F(ab')2 || [[Fab fragment|F(ab')<sub>2</sub> fragment]]
|-
| Fab' || [[Fab' fragment]]
|-
| scFv || [[Single-chain variable fragment]]
|-
| di-scFv || Di-[[single-chain variable fragment]]
|-
| 3funct || [[Trifunctional antibody]]
|-
| clFab || [[Chemically linked Fab]]
|-
| BiTE || [[Bi-specific T-cell engager]]
|}

'''source''' is the species on which the protein sequence of the antibody is based:
{| class = "wikitable"
|-
! source || output
|-
| a || [[موش صحرایی]]
|-
| e || [[همستر]]
|-
| i || [[نخستی‌سانان]]
|-
| o || [[موش]]
|-
| u || [[انسان]]
|-
| xi/a, xi/e, ''etc.'' || [[Chimeric antibody|Chimeric]] ([[موش صحرایی]]/[[انسان]]) ''etc.''
|-
| xi || [[Chimeric antibody|Chimeric]] ''[generic, use only if values above are not applicable]''
|-
| zu/a, zu/e, ''etc.'' || [[Humanized]] (from [[موش صحرایی]]) ''etc.''
|-
| zu || [[Humanized]] ''[generic, use only if values above are not applicable]''
|-
| xizu/a, xizu/e, ''etc.'' || [[Chimeric antibody|Chimeric]]/[[humanized]] hybrid ([[موش صحرایی]]/[[انسان]]) ''etc.''
|-
| xizu || [[Chimeric antibody|Chimeric]]/[[humanized]] hybrid ''[generic, use only if values above are not applicable]''
|-
| axo || [[موش صحرایی]]/[[موش]] hybrid
|}

'''target''' is the antigen at which the antibody is directed. This parameter takes free text as value, preferably including a wikilink such as '''target = <nowiki>[[TNF-α]]</nowiki>'''.

The drug name is followed by a "?" linked to [[Nomenclature of monoclonal antibodies]], saving the need to explain how each monoclonal antibody has been named.

'''Shortened Monoclonal antibody form:'''
<pre>
{{Drugbox
| type              = mab
| image             = 
| alt               = 
| mab_type          = <!-- mab, Fab, F(ab')2, Fab', scFv, di-scFv, 3funct, clFab, BiTE -->
| source            = <!-- a, e, i, o, u, xi/a, zu/a, xizu/a, axo, ... -->
| target            = <!-- antigen, NOT the code no. of the monoclonal antibody! -->

<!-- Clinical data -->
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| pregnancy_AU      = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US      = <!-- A / B            / C / D / X -->
| pregnancy_category=  
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled -->
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_status      = 
| routes_of_administration = 

<!-- Pharmacokinetic data -->
| bioavailability   = 
| protein_bound     = 
| metabolism        = 
| elimination_half-life = 
| excretion         = 

<!-- Identifiers -->
| CAS_number        = 
| ATC_prefix        = <!-- 'none' if uncategorised -->
| ATC_suffix        = 
| PubChem           = 
| DrugBank          = 

<!-- Chemical data -->
| chemical_formula  = 
| molecular_weight  = 
}}
</pre>

'''Full Monoclonal antibody template''' with extended fields:
<pre>
{{Drugbox
| type              = mab
| image             = 
| width             = 
| alt               = 
| image2            = 
| width2            = 
| alt2              = 
| imagename         = <!-- else may use drug_name -->
| drug_name         = <!-- else may use imagename -->
| mab_type          = <!-- mab, Fab, F(ab')2, Fab', scFv, di-scFv, 3funct, clFab, BiTE -->
| source            = <!-- a, e, i, o, u, xi/a, zu/a, xizu/a, axo, ... -->
| target            = <!-- antigen -->

<!-- Clinical data -->
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| licence_EU        = <!-- EMA requires brand name -->
| licence_US        = <!-- FDA may use generic name -->
| DailyMedID        = <!-- preference to licence_US -->
| pregnancy_AU      = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US      = <!-- A / B            / C / D / X -->
| pregnancy_category= 
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_status      = 
| dependency_liability = 
| routes_of_administration = 

<!-- Pharmacokinetic data -->
| bioavailability   = 
| protein_bound     = 
| metabolism        = 
| elimination_half-life = 
| excretion         = 

<!-- Identifiers -->
| CAS_number        = 
| CAS_supplemental  = 
| ATCvet            = 
| ATC_prefix        = <!-- 'none' if uncategorised -->
| ATC_suffix        = 
| ATC_supplemental  = 
| PubChem           = 
| PubChemSubstance  = 
| IUPHAR_ligand     = 
| DrugBank          = 
| ChemSpiderID      = 
| UNII              = 
| KEGG              = 
| ChEBI             = 
| ChEMBL            = 
| synonyms          = 

<!-- Chemical data -->
| chemical_formula  = 
| C= | H= | Ag= | As= | Au= | B= | Bi= | Br= | Cl= | Co= | F= | Fe= | Gd= | I=
| K= | Mn= | N= | Na= | O= | P= | Pt= | S= | Sb= | Se= | Sr= | Tc= | Zn= | charge=
| molecular_weight  = 
| smiles            = 
| StdInChI          = 
| StdInChI_comment  = 
| StdInChIKey       = 
| density           = 
| melting_point     = 
| melting_high      = 
| melting_notes     = 
| boiling_point     = 
| boiling_notes     = 
| solubility        = 
| specific_rotation = 
| sec_combustion    = 
}}
</pre>

===Vaccines===

Set the parameter '''type=vaccine'''. This allows the alternative parameters of the '''vaccine_type''' and '''target''' to be specified:
* '''target''' is freetext. Usually will be wikified by the editor to point to a specific page
* '''vaccine_type''' must be from the defined list of options as described at [[Vaccine#Types]], the infobox will provide standardised display and links as follows:
{|class="wikitable"
|-
! vaccine_type value !! Output
|-
| killed ''or'' inactivated  || Killed/Inactivated
|-
| attenuated || [[Attenuated virus]]
|-
| live || Live bacteria
|-
| toxoid || [[زهرواره]]
|-
| protein ''or'' protein subunit || [[Protein subunit]]
|-
| subunit || Subunit
|-
| conjugate || [[Conjugate vaccine]]
|-
| recombinant || [[Recombinant DNA|Recombinant Vector]]
|-
| DNA || [[DNA vaccination]]
|}

Where a vaccination product protects against more than one agent, please use the combination form of this infobox with '''type=combo''' (per [[#Combination products]]), and each '''classX=<nowiki>[[واکسن]]</nowiki>'''. 

'''Shortened Vaccine form:'''
<pre>
{{Drugbox
| type              = vaccine
| image             = 
| alt               = 
| target            = <!-- the antigen/bacteria/toxin/virus to protect against -->
| vaccine_type      = <!-- killed/attenuated/live/toxoid/protein subunit/subunit/conjugate/recombinant/DNA -->

<!-- Clinical data -->
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| pregnancy_AU      = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US      = <!-- A / B            / C / D / X -->
| pregnancy_category=  
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_status      = 
| routes_of_administration = 

<!-- Identifiers -->
| CAS_number        = 
| ATCvet            = 
| ATC_prefix        = <!-- 'none' if uncategorised -->
| ATC_suffix        = 
| PubChem           = 
| DrugBank          = 
}}
</pre>

'''Full Vaccine template''' with extended fields:
<pre>
{{Drugbox
| type              = vaccine
| image             = 
| alt               = 
| width             = 
| image2            = 
| alt2              = 
| width2            = 
| imagename         = <!-- else may use drug_name -->
| drug_name         = <!-- else may use imagename -->
| target            = <!-- the antigen/bacteria/toxin/virus to protect against -->
| vaccine_type      = <!-- killed/attenuated/live/toxoid/protein subunit/subunit/conjugate/recombinant/DNA -->

<!-- Clinical data -->
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| licence_EU        =  <!-- EMA requires brand name -->
| licence_US        =  <!-- FDA may use generic name -->
| DailyMedID        =  <!-- preference to licence_US -->
| pregnancy_AU      =  <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US      =  <!-- A / B            / C / D / X -->
| pregnancy_category= 
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_status      = 
| dependency_liability = 
| routes_of_administration = 

<!-- Identifiers -->
| CAS_number        = 
| CAS_supplemental  = 
| ATCvet            = 
| ATC_prefix        = <!-- 'none' if uncategorised -->
| ATC_suffix        = 
| ATC_supplemental  = 
| PubChem           = 
| PubChemSubstance  = 
| IUPHAR_ligand     = 
| DrugBank          = 
| ChemSpiderID      = 
| UNII              = 
| KEGG              = 
| ChEBI             = 
| ChEMBL            = 
}}
</pre>

===General notes about the fields===

None of the fields are obligatory.
DrugBank does not include every known drug and likewise <code>protein binding</code> may not be applicable to the drug (e.g. if only ever applied externally), so if these fields are not defined then their row is not shown.

Don't worry about getting all the fields — just do your best, and if you have any questions or suggestions, feel free to ask at [[Template talk:Drugbox]].

=== Parameter explanations ===

==== General ====
 | name = 
 | drug_name = 
* '''name''' – optional parameter to invoke a special use template (a separate Template:Drugbox/name page is created to store the template which is then transcluded into the drug article, view/discuss/edit button are displayed at top of drugbox) ''Not currently used''
* '''drug_name''' – an optional parameter that provides a title for the drugbox

===== Image =====

You can use the '''image''' to provide an illustration. These fields are optional, but it is helpful to provide an image if you can find one. Of course most images on the internet are copyrighted.  

You may specify the image name directly, else the template defaults to trying to use File:PAGENAME.png, where PAGENAME is the name of the drug article being written.

The '''alt''' parameter specifies the alt text for the image, used by visually impaired readers. See [[WP:ALT]].

There is also an optional '''width''' parameter you can add for the image. If your picture is far too big, then add a new line and specify a custom width like this: 

 <code> | image            = Aspirin.png
  | width            = 325</code>

When no width parameter is specified, it defaults to a width of 220.

Occasionally a second image might be added to show the chemical structure in a different format. Use the optional '''image2''' parameter for this. Hence the [[استامینوفن]] article uses:

 <code> | image            = Paracetamol-skeletal.png 
  | image2           = Paracetamol-3D.png</code> 

An '''alt2''' parameter specifies the alt text for the second image.
image2 generally uses the same width settings as the first image, i.e. as defined by '''width''' otherwise a default value of 220. A specific '''width2''' may though be applied.

==== Clinical data ====

 | tradename =  
 | Drugs.com =
 | MedlinePlus =

* '''tradename''' – comma separated list of tradenames
* '''Drugs.com''' – link to Drugs.com monograph
* '''MedlinePlus''' – MedlinePlus drug accession number

===== Pregnancy category =====

Pregnancy Categorisation has been previously declared using just the '''pregnancy_category''' parameter with a variety of markup styles used to indicate various countries and their classifications. Alternatively '''pregnancy_AU''' and '''pregnancy_US''' may be set to the fixed categories. For Australia values permitted are: A, B1, B2, B3, C, D or X (note if just set to 'B' then '''B?''' is shown). For US values permitted are: A, B, C, D or X.

Note the UK does not have official designated categorisations, but has both a variety of standard phrases with explanatory qualifications, plus many individual descriptions. '''pregnancy_category''' may still be used with the country-specific parameters as it is appended afterwards, allowing backwards compatibility for articles that only define this parameter, or for the future with free-text of other information.

Hence

 <code><nowiki>
  | pregnancy_AU = B1
  | pregnancy_US = C
  | pregnancy_category = Used in pregnancy against [[Pregnancy-induced hypertension|PIH]]
</nowiki></code>

gives

B1 <small>([[استرالیا]])</small> C <small>([[ایالات متحده آمریکا]])</small> Used in pregnancy against [[Pregnancy-induced hypertension|PIH]]

===== Legal status =====

Legal status has been previously declared using just the '''legal_status''' parameter with a variety of markup styles used to indicate various countries and their classifications. Alternatively '''legal_AU''', '''legal_CA''', '''legal_UK''' and '''legal_US''' may be set to the fixed options in the table hereafter. The template will ensure the categorisation is shown correctly capitalised, use Unicode Rx symbol and add a linked 2-letter country code as per [[ویکی‌پدیا:شیوه‌نامه]]. '''legal_status''' may still be used with the country-specific parameters as it is appended afterwards, allowing backwards compatibility for articles that only define this parameter, or for the future with free-text of other information.

Hence

 <code><nowiki>
  | legal_AU     = S2
  | legal_UK     = gsl
  | legal_US     = Rx-only
  | legal_status = Not marketed in [[آسیا]]
</nowiki></code>

gives

S2 <small>([[استرالیا]])</small> GSL <small>([[بریتانیا]])</small> [[Prescription drug|{{Unicode|℞}}<small>-only</small>]] <small>([[ایالات متحده آمریکا]])</small>  Not marketed in [[آسیا]]

Note: if a drug is restricted everywhere to prescription-only, please set '''legal_status = Rx-only''' rather than similarly define for each and every country ('Rx-only' is specifically recognised by legal_status and shows as ''{{Unicode|℞}} P<small>rescription only</small>'')  

{|class="wikitable"
|-
!Abbreviation<br/>(options) !!Meaning
|-
! legal_status !! Anywhere
|-
| Rx-only || ℞ Prescription only
|-
! legal_AU !! Australia<br/>(see [[Standard for the Uniform Scheduling of Drugs and Poisons|SUSDP]])
|-
|Unscheduled || Unscheduled/exempt
|-
|S2 || Schedule 2 Pharmacy Medicine
|-
|S3 || Schedule 3 Pharmacist Only Medicine
|-
|S4 || Schedule 4 Prescription Only Medicine
|-
|S5 || Schedule 5 Caution 
|-
|S6 || Schedule 6 Poison 
|-
|S7 || Schedule 7 Dangerous Poison 
|-
|S8 || Schedule 8 Controlled Drug
|-
|S9 || Schedule 9 Prohibited Substance 
|-
! legal_CA !! Canada
|-
|OTC || Over the counter
|-
|Rx-only || {{Unicode|℞}} Prescription only
|-
| Schedule I || rowspan=8 | See [[Controlled Drugs and Substances Act]]
|-
| Schedule II
|-
| Schedule III
|-
| Schedule IV
|-
| Schedule V
|-
| Schedule VI
|-
| Schedule VII
|-
| Schedule VIII
|-
! legal_UK !! United Kingdom
|-
|GSL || General Sale List
|-
|P || Pharmacy Medicine
|-
|POM || Prescription Only Medicine
|-
|CD || Controlled Drug; if known may specify:
|-
| CD Lic || rowspan=6 | See [http://www.opsi.gov.uk/si/si2001/20013998.htm Misuse of Drugs Regulations 2001 (as amended)]
|-
| CD POM
|-
| CD No Reg POM
|-
| CD (Benz) POM
|-
| CD (Anab) POM
|-
| CD Inv POM
|-
! legal_US !! United States
|-
|OTC || Over the counter
|-
|℞-only<br/>Rx-only || Prescription only; if appropriate may specify:
|-
| Schedule I || rowspan=5 | See [[Controlled Substances Act]]
|-
| Schedule II
|-
| Schedule III
|-
| Schedule IV
|-
| Schedule V
|-
|}

===== Dependence liability =====

An optional parameter of '''Dependence liability''' allows opioids or benzodiazepines to be flagged with the risk of becoming dependent upon them, although in many cases this may be somewhat subjective. Drugs should be rated as ''Low'', ''Medium'', ''High'' or ''Extremely high'':

 <code> | dependency_liability= High</code> 

===== Licensing information =====

There are two major licensing authorities that make drug information easily accessible: The [[ایالات متحده آمریکا]] [[اداره مواد غذائی و داروئی ایالات متحده آمریکا]] (FDA) and the [[European Medicines Agency]] (EMA). NB: The word "licence" is the noun in British English, "license" is the verb.

The FDA "Label Information" and the EMA "Product Information", where available, are very detailed. There is material aimed at the professional and also plain-English consumer information. These are excellent reliable source for article information but also contains much that makes it a worthwhile "External link" since there is no way one can include all the info. Both sites work using of the brand name of the drug but the FDA site also allows searches with the generic name (active ingredient), which lists generic variants where they are licensed. 
<pre>
  | licence_EU = <!-- EMA requires brand name --> 
  | licence_US = <!-- FDA may use generic name -->  
</pre>
Lists of products and the parameter term to use may be easily searched for: 
* European Public Assessment Reports: [http://www.ema.europa.eu/sitemap.htm SiteMap], authorised products A–Z: [http://www.ema.europa.eu/htms/human/epar/a.htm human], [http://www.ema.europa.eu/htms/vet/epar/a.htm veterinary]
*: When items are composed of more than one word, '''licence_EU''' uses adjoined words (i.e. no spaces); e.g. ''infanrixpenta'' for Infanrix Penta.
* Drugs@FDA [http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm?fuseaction=Search.Search_Drug_Name Search by Drug Name or Active Ingredient]
*: Where items are composed of more than one word, '''licence_US''' requires an underscore '_' in place of any spaces; e.g. ''Acyclovir_Sodium''.

More patient friendly than the FDA's pages is [[Daily Med]] which reproduces the same details. The '''DailyMedID''' parameter, where specified, is shown in preference to the licence_US direct FDA link. Daily Med entries may be located at [http://dailymed.nlm.nih.gov/dailymed/about.cfm Search By Drug Name], e.g. for [[فوروزماید]]
<pre>
  | DailyMedID = 3940
</pre>

====Pharmacokinetic data and routes of administration====

These parameters should be filled in because they contain important inforamtion about a drug. Use wikilinks for values that the general reader might not understand (e. g. [[کبد]], [[CYP3A4]], [[intraperitoneal]]).

  | bioavailability   = 
  | protein_bound     = 
  | metabolism        = 
  | elimination_half-life = 
  | excretion         = 
  | routes_of_administration = 

==== Identifiers ====

=====DrugBank=====

The [[DrugBank]] primary accession number (consisting of a 2 letter prefix (DB) and a 5 number suffix). Secondary accession numbers with a 4 letter suffix (APRD, EXPT, BIOD, NUTR) should not normally be used.

=====PubChem=====

When available, the [[پاب‌کم]] ''compound'' identifier (CID) should be used because it is unique for each chemical compound:
<pre>
  | PubChem        = 4091  <!-- Metformin -->
</pre>
Make sure you choose the right CID: Often PubChem compound entries differ only very slightly, for example by an additional hydratation water or by a carbon atom with unspecified stereochemistry.

If no CID is available, which is usually the case when there is no structural information on PubChem, you may use one of the ''substance'' identifiers (SIDs):
<pre>
  | PubChemSubstance    = 10099  <!-- Etanercept -->
</pre>
The drugbox won't display both CID and SID to avoid list cruft.

===== Other identifiers =====

The following identifiers are also supported:
* [[International Union of Basic and Clinical Pharmacology]] ligand (<code> | IUPHAR_ligand = </code>)
* [[DrugBank]] identifier (<code> | DrugBank = </code>)
* [[کم‌اسپایدر]] identifier (<code> | ChemSpiderID = </code>)
* [[Unique Ingredient Identifier]] (<code> | UNII = </code>)
* [[Kyoto Encyclopedia of Genes and Genomes]] (<code> | KEGG = </code>)
* [[Chemical Entities of Biological Interest]] (<code> | ChEBI = </code>)
* [[ChEMBL]] (<code> | ChEMBL = </code>)
* [[NIAID ChemDB]] for HIV/AIDS drugs (<code> | NIAID_ChemDB = </code>)
* [[مترادف]]s (<code> | synonyms = </code>) – '''Do not include''' an indiscriminate list of synonyms.

===== ATC, ATCvet and CAS =====

{{see|Wikipedia:WikiProject Pharmacology/Style guide#Use ATC codes}}
Where the drug is not included in ATC coding system (as opposed to its value just not been entered into the template) then set '''ATC_prefix''' to 'none', and the article is automatically added to [[:Category:Drugs not assigned an ATC code]] rather than [[:Category:Drugboxes with an unspecified ATC code]]:
<pre>
  | ATC_prefix        = none
</pre>
  
Additional ATC or CAS codes may be included with the optional  '''ATC_supplemental''' & '''CAS_supplement''' parameter as a comma-separated lists. CAS or ATC templates may be used to have these additional codes link to the relevant databases:
<pre>
  | CAS_supplemental ={{CAS|427-51-0}} (acetate)
  | ATC_supplemental ={{ATC|M02|AA15}}, {{ATC|S01|BC03}}  
</pre>
Adds the following linked codes:
 For CAS -  {{CAS|427-51-0}} (acetate)
 For ATC - {{ATC|M02|AA15}}, {{ATC|S01|BC03}}

Veterinary drugs are placed in a slightly different classification system, [[Anatomical Therapeutic Chemical Classification System#ATCvet|ATCvet]]. The code may be specified as ATCvet by setting the parameter '''ATCvet''' to 'yes'. Do not include the leading 'Q' in '''ATC_prefix''':
<pre>
  | ATCvet            = yes 
  | ATC_prefix        = N05
  | ATC_suffix        = AX90
</pre>

===== <tt>verifiedrevid</tt> and <tt>XXX_Ref</tt> parameters =====

<tt>verifiedrevid</tt>, as well as parameters like <tt>CASNo_Ref</tt>, <tt>StdInChI_Ref</tt>, etc., are used by the [[Wikipedia:WikiProject Chemicals/Chembox validation|Chembox/Drugbox validation process]].

==== Chemical data ====

=====Chemical formula=====

You can provide the chemical formula as either the default

 <code> | chemical_formula =</code> 

or by setting atom counts for each element, in these parameters:

 <code> | C= | H= | Ag= | As= | Au= | B= | Bi= | Br= | Cl= | Co= | F= | Fe= | Gd= | I=
  | K= | Mn= | N= | Na= | O= | P= | Pt= | S= | Sb= | Se= | Sr= | Tc= | Zn= | charge=</code>

E.g.

 <code> | C=2 | H=6 | O=1</code>

gives

Formula   <font color="000000">[[کربن]]</font><sub>2</sub><font color="4D4D4D">[[هیدروژن]]</font><sub>6</sub><font color="742323">[[اکسیژن]]</font>

Irrespective of the order of assigning values to the constituent parameters, the formula is displayed with elements in the hereinbefore order. The charge parameter, if defined, is shown superscripted. 
 
E.g.

 <code> | C=2 | O=1 | H=6 | charge=+</code>

is identical to next line

 <code> | C=2 | H=6 | O=1 | charge=+</code>

giving

Formula   <font color="000000">[[کربن]]</font><sub>2</sub><font color="4D4D4D">[[هیدروژن]]</font><sub>6</sub><font color="742323">[[اکسیژن]]</font><sup>+</sup>

=====Other chemical data=====

Additional chemical data fields are [[Simplified molecular input line entry specification|SMILES]] and standard [[شناسه شیمیایی بین‌المللی|InChI]] (optionally oncluding a comment and standard InChIKey).

  | smiles            =
  | StdInChI          =
  | StdInChI_comment  =
  | StdInChIKey       =

===== Physical data =====

This is an entirely optional section, and for most drugs is '''not helpful''' to the wider readership. Only include if information of particular interest for the drug as to its chemical propersites (e.g. in its manufacture or as an important chemical in its own right, e.g. [[استیل‌سالیسیلیک اسید]]). If any of the following optional parameters are defined then a new section header of 'Physical data' is shown.
 
  | density           = 
  | melting_point     = 
  | boiling_point     = 
  | solubility        = 
  | specific_rotation = 
  | sec_combustion    = 

The template will add the following to the numeric values provided:
*'''Density''' - added 'g/cm<sup>3</sup>'
*'''Melting''' or '''Boiling''' points - added '°C' along with calculated converted value in °F.
*'''Solubility''' - added 'mg/mL (20&nbsp;°C)'

Hence:

 <code> | melting_point = 100</code>

gives:

Melting point   100&nbsp;°C (212&nbsp;°F)

In addition, where the melting point occurs over a range of temperatures, use '''melting_high''' for the upper value.

Hence:

 <code> | melting_point = 100
  | melting_high  = 104</code>

gives:

Melting point   100–104&nbsp;°C (212–219&nbsp;°F)

Comments can be added to the melting and boiling point entries using '''melting_notes''' and '''boiling_notes'''.

Hence:

 <code> | boiling_point = 100
  | boiling_notes = (sublimes)</code>

gives:

Boiling point   100&nbsp;°C (212&nbsp;°F) (sublimes)

===See also===

* [[ویکی‌پدیا:ویکی‌پروژه داروشناسی]] for WikiProject page

<includeonly>

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[[Category:Medicine infobox templates]]

<!-- ADD INTERWIKIS BELOW THIS LINE -->
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[[it:Template:Drugbox]]
[[ja:Template:Drugbox]]
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[[ml:ഫലകം:Drugbox/doc]]
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</includeonly>